Recently, abnormalities in neuroendocrine function have been suspected to be responsible for impaired patient energy and mood
3.1.9 Epigallocatechin-3-gallate (EGCG) and epicatechin EGCG, a polyphenol abundant in green tea extract, is a STAT1 inhibitor.EGCG prevents cisplatin cytotoxicity through anti-apoptotic and antioxidant effects ( in vitro and ex vivo (Xie et al., 2004).EGCG acts through phosphatidylinositol 3-kinase (PI3K)/Akt signalling in cochlear NSCs to promote cell growth and neuronal differentiation, which can be used for the treatment of hearing loss (Zhang et al., 2016), and has an important protective mechanism against cochlear oxidative damage
Its safety is relatively high, but when using it, attention should still be paid to issues such as skin sensitivity and usage concentration
If nausea becomes problematic, consider staying at this dose for 6 to 8 weeks instead of 4 before escalating further
BPC-157 consistently holds the largest body of preclinical gut health research by volume