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Binding to this allosteric site can still influence the sensitivity and activity of the receptor, but could lead to drugs with fewer off-target side-effects, since GLP-1 is involved in many different metabolic signalling pathways
Researchers point to several reasons for this variation, including differences between specific GLP-1 medications, individual mental health history, the presence of eating disorders or mood disorders, and differences in dosage, duration of use, and overall health
Similar finding was reported by Nassar and collaborators who studied twenty-one patients on KDT, and their results showed more than 50% reduction in their seizures 23
Millet N, et al
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