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While semaglutide works powerfully on appetite and metabolism, its effects on brain chemistry can occasionally create emotional shifts

Nature (2003) 422(6928):1736

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We also summarize newly proposed mechanisms associated with hepatoprotection and tumor suppression, such as attenuation of hepatocellular stress through inhibition of the NEDD9/FAK/AKT cascade and a potential role in cell-cycle regulation via the HDAC/p21 axisalthough the latter remains to be validated in MASLD-specific models

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