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KPV inhibitsNF-B activation at nanomolar concentrations through stabilization of IB- and prevention of p65RelA nuclear translocation[13]
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For example, preconditioning with low doses of lipopolysaccharides (LPS), a component of bacteria cell walls known to trigger an immune response, has demonstrated neuroprotective effects including enhancing cellular resilience, supporting neuronal health, and promoting a monocyte phenotype that aids in tissue repair rather than causing damage [27, 107, 108]
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