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Mishra P, Paital B, Jena S, Swain SS, Kumar S, Yadav MK, et al

Structural requirements of flavonoids and related compounds for aldose reductase inhibitory activity

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There is also some limited evidence suggesting that individuals who carry certain polymorphisms in genes involved in vitamin C transport and detoxification mechanisms may have lower plasma vitamin C concentrations even with high vitamin C intakes (see also Vascular complications of diabetes mellitus) (reviewed in 27)