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Overall, further evidence is needed to define the optimal sequencing of these two agents in adults with CKD and T2D with or without overweight/obesity
However, untreated or poorly controlled hypothyroidism may make weight loss more difficult, so thyroid hormone levels should be appropriately managed before and during treatment
Constipation was reported in 24.2% of people taking semaglutide, compared to 11.1% taking the placebo
This work was supported by the National Natural Science Foundation of China (Grant No
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