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Vos T, Lim SS, Abbafati C et al

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[9] Because B vitamins are water-soluble, excess amounts are excreted in urine, which can lead to a noticeable change in urine color

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I started taking NAC and the headache went away, but the NAC caused constipation since Glutathione isnt well-absorbed taken orally, I figured out that a patch would be a good solution since I read that it is used intraveniously to help people heal after surgery and also that NAC is the only thing that helps if someone has acetaminafen liver toxicity So I started the Glutathione patch and the headaches have not come back for several months