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Glutathione injections work by delivering a high dose of the antioxidant directly into the muscle
The upregulation of GPX2 leads to the clearance of H 2 O 2 , the inhibition of apoptosis, and the weakening of oxidative stress
It is worth mentioning that ebselen does not contribute to the bioavailable selenium pool required for the biosynthesis of selenoproteins including seleno-GPxs and therefore its ability to detoxify hydroperoxides under cellular conditions can exclusively be attributed to GPx mimicking activity [77, 79]
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