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Clinically significant safety concerns include heart rate elevation, risk of hypoglycaemia when combined with insulin or sulfonylureas, delayed gastric emptying, and a class-relevant caution regarding thyroid C-cell tumours
limits semaglutide reimbursement to BMI 35 kg/m, excluding many high-risk patients
Patients should discuss the specific risks, benefits, and current availability of compounded medications directly with their prescribing clinician before beginning treatment, and should ask about whether an FDA-approved medication may be appropriate for their situation
Always ensure at least 72 hours have passed between injections to avoid an increased risk of side effects from having too much medication in your system at once
Mitochondrial catalase and oxidative injury
