PMID: 22682224 | doi:10.1016/j.cmet.2012.04.022 Yoshino J et al
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Nausea from vitamin B12 supplements is often related to inactive ingredients such as binders, fillers, or excipients rather than the vitamin itself
(Source) When this enzyme is present in great concentration within fat cells and is highly expressed, obesity is inevitable: In the study by Kannt and colleagues, NNMT expression is increased ~2-fold in subcutaneous and omental adipose tissue of type 2 diabetic subjects (men and women), compared to healthy controls Importantly, interventions that increase insulin sensitivity, such as exercise and bariatric surgery, also decreased expression of NNMT in adipose tissue For this reason alone, scientists have been interested in every possible method for inhibiting NNMT expression: We report that NNMT expression is increased in [white adipose tissue (WAT)] and liver of obese and diabetic mice

It has glutathione, but it also has plenty of other ingredients that support your health at a cellular levelNAD+ and CoQ10 are both essential enzymes that support healthy aging, vitamin B12 helps with cognitive functioning and energy levels, and lactoferrin is a protein that comes from colostrum and promotes gut health