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9 These diabetes medicines are potentially underused in patients who would benefit from them
Fosgerau K, Hoffmann T
The glucagon receptor activation (paradoxically) adds metabolic benefits when paired with GLP-1 and GIP , such as promoting energy expenditure and fat oxidation, possibly combating the decrease in basal metabolic rate that accompanies weight loss, and helping reduce liver fat
By contrast, the DIO rats tolerated much higher doses (up to 100 nmol/kg/day) of GEP44 with no indication of malaise
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