Major Surgery: You should typically stop both supplements and GLP-1 medications before undergoing surgery, as they can affect anesthesia and blood sugar stability
While Ozempic and Zepbound share similarities, they target different biological pathways: Ozempic (semaglutide): A GLP-1 receptor agonist that mimics glucagon-like peptide-1 (GLP-1)
One such trial found that, on average, Mounjaro reduces BMI by 25.3% by week 88, or roughly 20 months
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Collectively, this indicates a role for CNS GLP-1R populations to mediate food intake suppression by pharmacologic, and to a lesser degree physiologic, GLP-1R agonism