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Dealing with the standard titration schedule The standard semaglutide titration follows a step-up protocol designed to minimize gastrointestinal side effects

When intake and interference are accounted for and the elevation persists, the result is interpreted by weighing hepatic, renal, hematologic, malignant, and functional possibilities

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Because the injections are given infrequently with a very small needle (typically a 25-gauge needle is adequate), this is not usually a very unpleasant experience for the cat