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The control population consisted of patients on placebo or not using GLP-1 agonists

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Three small cohort studies 148,149,150 examined associations between GLP-1RA use and metabolic changes in adults with a diagnosis of schizophrenia and comorbid diabetes and/or obesity on antipsychotics

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Takeaways: - Cryoneurolysis with current argon-based methods may not reliably reach low enough temperatures in large proximal nerves

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In the TRIUMPH-1 Phase 3 trial, participants on the maximum dose of retatrutide (12 mg) lost an average of 28.3% of their body weight after 80 weeks, and up to 30.3% after 104 weeks in the study extension

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