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Participants: A total of 201 adolescents aged 1218 years were randomized to receive once-weekly semaglutide (2.4 mg) or placebo
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5.2 Cellular crosstalk Intestinal epithelial cells (IECs) constitute a critical physical barrier that segregates the intestinal lumen, with its diverse contents, including digested nutrients, commensal microbiota, and potential pathogens, from the underlying mucosal immune system (164)
The high demand for effective weight loss treatments, coupled with increasing awareness of Semaglutide's benefits, contributed to its market leadership, despite the presence of other GLP-1 drugs
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