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One non-randomized open-label study, published over 2 separate articles, showed that 4-week liraglutide led to an improvement in a test of executive functioning (and possibly other cognitive measures) 178 and related increase in fronto-striatal volumes 179 , partly moderated by BMI and insulin resistance changes, in 19 people diagnosed with bipolar disorder or major depression

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It works in synergy with other anti-oxidants and in particular helps to regenerate the antioxidant capacity of vitamins C and E

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GSK3 overexpression abrogates the protective effects of semaglutide, while GSK3 knockdown mimics its actions, establishing GSK3 as a mediator of GLP-1