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Changes in GSH levels with time post dose were calculated as the difference in GSH/Cr peak ratios for each subject at each time point (GSH/Cr post dose GSH/Cr baseline ), or similarly, the difference in absolute GSH for each subject at each time point
However, at this point no drug can be recommended for human use before its utility has been confirmed in convincing clinical trials. Guarente, Sinclair, and Kromer Surprisingly, when it comes to these clinical trials, NAD+ precursors seem to have the most wide-ranging effects applicable to counteracting the aging process in humans
Dosage plays a role
The activation of pro-migratory signals (FAKpaxillin) and pro-angiogenic factors (VEGF, EGR-1, nitric oxide) by BPC-157is a double-edged sword
Development 137 , 5361 (2010)
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