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S-adenosylmethionine (SAMe), an amino acid derivative important in liver metabolism, and extracts from milk thistle ( Silybum marianum ), have been investigated (alone and in combination) in dogs for their liver-protecting properties and are currently used as part of treatment for a variety of liver diseases in dogs
(1994) Glutathione and morbidity in a community-based sample of elderly
The importance and regulation of hepatic glutathione. Yale Journal of Biology and Medicine
(2015) documented that oral glutathione at 250-1000 mg daily for 6 months did increase blood, erythrocyte, and lymphocyte glutathione levels, though the magnitude of increase was smaller than injectable or IV routes (Richie et al., 2015)
Please consult your veterinarian with any concerns regarding your dog's specific needs, medical conditions, and before implementing any diet, supplement, or exercise changes based on information found on this site.
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