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Research Background In preclinical (animal and in vitro) models, BPC-157 has been studied as a cytoprotective peptide of interest in gastrointestinal, musculoskeletal, and vascular research
Phase II clinical trials in patients with sarcoidosis-related small fiber neuropathy demonstrated significant increases in corneal nerve fiber density (a reliable surrogate marker for systemic small fiber health) alongside meaningful reductions in neuropathic pain scores
For references and more information , see the section on Cardiovascular disease in the Folate article
Ultimately, 14 RCTs 10,11,1526 and one open-label clinical trial 12 met the inclusion criteria
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