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Ozempic became a popular off-label weight loss medication, and subsequently, the FDA approved semaglutide under the trade name Wegovy to treat obesity Unfortunately, people using Ozempic for weight management, and outsiders following semaglutide users weight loss journey, sometimes notice facial changes on the semaglutide, and not for the better

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Novo Nordisk reined in its growth forecasts for the year in its second-quarter financial results update, blaming "persistent use of compounded GLP-1s, slower-than-expected market expansion, and competition." Compounding of semaglutide should have come to a halt in the US since the drug was removed from the FDA list of medicines in short supply, but various companies continue to provide compounded GLP-1s under a loophole that allows the sale of 'personalised' formulations