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Hunter DJ, March L, Chew M
Fmoc amino acids were purchased from Protein Technologies or Novabiochem, Fmoc-(S)-2-methyl Biphenylalanine, Fmoc-(S)-2-ethyl-4-methoxy biphenylalanine and Fmoc-(S)-2-fluoro-R-methylphenylalanine were synthesized as described previuosly 18
This leads to polarization of adipose tissue macrophages toward the pro-inflammatory M1 phenotype, releasing large amounts of pro-inflammatory mediators, forming a vicious cycle of inflammation-metabolic disorder
1 2 Obesity
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