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The TRANSCEND-T2D-1 trial adds a second pressure point: 16.8% body weight reduction in patients with type 2 diabetes, a population that consistently underperforms on weight-loss endpoints with existing agents
Not all formulations contain enough B12 to fully offset absorption losses, especially at higher semaglutide doses
In Retatrutide trials, 91.7% of participants achieved at least 10% body weight reduction at the highest dose
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