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2019;94(3):E7880

ii) increased AMPK also inhibits mitochondrial glycerol-3-phosphate dehydrogenase (mGPD), leading to an increase in cytosolic NADH, which both stimulates the conversion of pyruvate to lactate, and simultaneously decreases gluconeogenesis

This dual agonist mechanism represents a major advancement in metabolic research and forms the foundation for any Retatrutide vs Tirzepatide analysis

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