Comparative analysis of outcomes between those who used GLP-1 RAs in the first 3 months post-transplant and continued from 3 to 6 months, versus those who did not use GLP-1 RAs during either period, yielded similar results (Supplemental Table 9)
A member of the G-protein-coupled receptor superfamily, 9 the binding of GLP-1 to GLP-R on pancreatic -cells leads to an increase in insulin secretion, mainly due to an increase in cAMP production
In particular, heart mitochondria from mice with selective TSPO deletion in hearts undergo MPT and are as sensitive to ischemiareperfusion injury as hearts from control mice
Dehestani B, Stratford NR, le Roux CW
In the phase 2 trial, the most common retatrutide side effects were digestive: nausea, diarrhoea, vomiting, and constipation