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10.1042/bj20100409 Biochem

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]

Amylin signaling in the brain affects appetite and metabolism differently than GLP-1 signaling

Using our previously described DMS library that covers all possible point mutations within 10 of the IMiD-binding site of CRBN 49 , we found that rac -dHTC1 and SR-1114 are sensitive to similar CRBN mutations (Extended Data Fig

70 BCKDK inhibitors are also effective in attenuating insulin resistance in mouse models of obesity, and the development of a new generation of more powerful BCKDK inhibitors is important for diseases that require inhibition of BCAA catabolism