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Trial participants typically receive close monitoring, support, and follow-up that may not reflect typical clinical practice

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Some C/EBP family members, such as the C/EBP homologous protein (CHOP), form inactive heterodimers with C/EBP and C/EBP

Within the geroscience framework 16 , the accelerated-aging phenotype in PWH provides an ideal clinical model to evaluate candidate geroprotective therapies, with findings potentially relevant to the general aging population