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Liraglutide vs insulin glargine and placebo in combination with metformin and sulphonylurea therapy in type 2 diabetes mellitus: a randomized controlled trial (LEAD-5 met SU)

GLP-1 receptor agonists like dulaglutide or exenatide overlap directly with semaglutide's mechanism

This delay is particularly critical for patients with advanced maternal age (AMA) or diminished ovarian reserve (DOR), for whom any postponement may result in an irreversible decline in reproductive potential

Any new or unexpected symptoms should be discussed promptly, and self-management without medical oversight is strongly discouraged

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