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315 The results showed that, in the OA rat model, liraglutide could activate the PKA/CREB signaling pathway and inhibit the inflammatory response through this pathway, thereby alleviating OA symptoms
As a consequence, GF mice have energy-depleted colonocytes due to the absence of their SCFA energy source, butyrate (169)
However, they did not test ARA-290 as a treatment for sciatica caused by a herniated disc, spinal stenosis, or lumbar nerve compression
Presented for research literature review only Cartledge JC et al
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