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Pereira and Martel, 2014
One detail is easy to miss
doi: 10.1073/pnas.1002611107, 84 ReidG.CharbonneauD.ErbJ.KochanowskiB.BeuermanD.PoehnerR.et al
Oral administration of GSH is not very effective, however, because it is poorly absorbed through digestion and insufficient amounts cross the blood-brain barrier
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[3] The proposed mechanism involves B12 altering the gene expression of skin bacteria ( Cutibacterium acnes ), leading to increased inflammatory compounds
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