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The liver benefits were seen in nearly 1.5-year results from the first part of the ongoing global Phase 3 ESSENCE clinical trial (NCT04822181)

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Downstream processing Purification This unit operation removes impurities from the crude peptide following the cleavage step

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For example, MarR is glutathionylated under oxidative conditions, 89 suggesting that other thiol-containing proteins, potentially including antibiotic targets or regulators, may also be modified in vivo