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The percent (%) cytotoxicity was determined using the following formula for each given experimental treatment: Cytotoxicity (%) = 100 [(Experimental Culture Medium Background)/(Maximum LDH Release Culture Medium Background)]
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In addition, there is a strong correlation between insulin and Nrf2 signaling pathways both in the periphery and the brain but merely few of them have focused on elucidating their inter-connective role in AD (Rahman et al
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In this context, elevated levels of proinflammatory cytokines, such as IL-1 and TNF-, drive excessive activation of both peripheral and central immune systems
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