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Most research protocols don't require accounting for overfill at the individual-dose level
doi:10.1016/S0092-8674(00)81883-8 57
doi: 10.1186/s12951-023-02146-0 115 KwakGKimDNamGHWangSYKimISKimSHet al
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Upon intravenous administration, nanoparticles are highly susceptible to protein corona formation, which can mask targeting ligands and trigger rapid opsonization (69, 70)
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