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By comparison, GLP-1 monotherapy alone achieves 14.9% (STEP 1) to 20.9% (SURMOUNT-1) of body weight loss
[15] (Conversely, chronic inflammation can deplete glutathione levels.) A depletion in glutathione levels has been implicated with higher levels of thyroid antibodies and may contribute to Hashimotos
Its also a useful conversation starter with patients who feel like theyve failed on a GLP-1, when in reality, their response may have been shaped by factors completely outside their control
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