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Importantly, tolerance to side effects does not mean tolerance to therapeutic benefits

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Switching for cardiovascular protection If the cardiovascular outcome data from the SELECT trial influenced your switch decision, the target formulation is typically Wegovy at 2.4 mg weekly

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PubMed To put that 79% risk reduction in context, the landmark Diabetes Prevention Program study from the early 2000s showed that intensive lifestyle intervention reduced diabetes risk by 58% and metformin reduced it by 31%