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Cardiac fibrosis assessed by late gadolinium enhancement (LGE) with cardiac magnetic resonance (CMR) is positively correlated to ventricular tachyarrythmias and SCD in various cardiomyopathies 5,6,7
The hypothalamus, a brain region targeted by GLP-1 drugs and crucial in hormonal regulation, may mediate such systemic effectsan area ripe for neuroscientific and endocrinological research
Retinol
Most GLP-1s are administered via subcutaneous injection using a pre-filled pen
Niimura et al., The experimental value of zebrafish as an animal model for in vivo drug discovery has grown rapidly due to their ease of assessment, large clutch size, and ability to recapitulate human disease conditions (MacRae and Peterson, in vivo , demonstrating that otoprotective drug discovery in zebrafish translates to mammalian systems (Owens et al., 2011)
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