In the rare disease space, Viking is developing VK0214, a novel, orally available, small molecule selective thyroid hormone receptor beta agonist for the potential treatment of X-linked adrenoleukodystrophy (X-ALD)
Compared with GLP-1 alone, dual agonism may provide: greater appetite reduction for some patients improved insulin sensitivity additional metabolic benefits Clinical trials demonstrated substantial weight loss in many patients using tirzepatide for obesity management
Because these symptoms are so often seen in association with other diseases, these signs and symptoms are not part of the diagnostic criteria for SLE
10.1161/01.STR.0000181779.83472.35 189 YudkoffM.DaikhinY.HorynO.NissimI
GLP-1 and the Science of Aging Glucagon-like peptide-1 (GLP-1) receptor agonists, primarily known for their roles in managing diabetes and obesity, are now being explored for their potential to extend healthy lifespan and combat age-related diseases