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Algunos avances intentan revertir esta situacin: el frmaco Rybelsus combina semaglutida con un compuesto que facilita su absorcin intestinal, aunque requiere tomarse en condiciones muy especficas y solo est aprobado para tratar la diabetes

2013 May

10.1186/s12937-016-0217-2 4 AnfusoC

Eat Smaller, More Frequent Meals Since semaglutide slows digestion, consuming large meals can contribute to nausea

Of note, over the last years, an array of unimolecular GLP1-based poly-agonists, with different mechanisms of action, have been developed and experimentally validated for the treatment of metabolic syndrome, holding superior efficacy relative to conventional GLP1-RA 33,34,35