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Scioli et al

Pogribna M, Melnyk S, Pogribny I, Chango A, Yi P, James SJ: Homocysteine metabolism in children with Down syndrome: in vitro modulation

Sample preparation and quantification for carnitine, TMAO, and -butyrobetaine of cardiovascular disease patient For optimal extraction, 180 L or 190 L of methanol spiked with 200 ng/mL of isotopically-labeled internal standards (d3-carnitine and d9-TMAO) was added to 20 L of plasma or 10 L of urine samples, respectively

Understanding these mechanisms is very important in the prevention and treatment of many diseases