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The peptide is now in an aqueous environment, making it far more susceptible to oxidation and degradation
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doi: 10.3892/etm.2019.7347 36 HadjiyanniISiminovitchKADanskaJSDruckerDJ
[1] This mechanism reduces the risk of hypoglycemia when used alone, though this risk increases when combined with insulin or sulfonylureas
The onset of metformin-associated lactic acidosis is often subtle, accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, somnolence, and abdominal pain
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