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Wegovy carries an additional indication for cardiovascular risk reduction in adults with obesity and established cardiovascular disease, based on outcomes from the SELECT trial

In small proof-of-concept phase 2 randomized controlled trials (RCTs) in patients with biopsy-confirmed MASH, liraglutide at 1.8 mg/day for 48 weeks (201), semaglutide at 0.4 mg/day for 72 weeks (202), and tirzepatide at 15 mg/week for 52 weeks (203) have been reported to achieve placebo-corrected percentages of participants meeting the criteria for resolution of MASH without worsening fibrosis by 30% (P = 0.019), 42% (P 10%) may lead to diabetes remission (237)

This article examines the evidence, risks, and medical guidance to help patients make informed decisions and communicate openly with healthcare professionals about substance use during Wegovy treatment

Aim for a protein target of roughly 1.2 to 1.6 g/kg and pair that with resistance training at least twice a week to help preserve muscle

Messing with syringes, reusing needles, and guessing dosages is a hard no