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Within hepatocytes, GL is partially metabolized by lysosomal -D-glucuronidase to form 3MGA (Ploeger et al., 2001)
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Yang WS, SriRamaratnam R, Welsch ME, Shimada K, Skouta R, Viswanathan VS, et al
Perhaps we can also use GLP-1 agonists in concert with other medications we already have, like methadone and buprenorphine (one of the ingredients in a medication called Suboxone), which are used to treat opioid addiction
Tesamorelin is not appropriate for patients with active malignancy, uncontrolled diabetes, proliferative retinopathy, or during pregnancy or breastfeeding
