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A systematic review and meta-analysis published in the Journal of Obesity found that HCA was associated with a small, statistically significant difference in short-term weight loss compared with placebo
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Unlike prior studies of AMD development that were limited to patients with diabetes, the authors wrote in their paper, their findings suggest that GLP-1 drugs "may be associated with reduced risk even in individuals with obesity but not diabetes, potentially supporting a protective benefit independent of glycemic control and mitigating diabetes as a confounding factor.
Additionally, individuals with a history of certain health conditions or sensitivities to medication may respond differently to each drug, making it important to discuss any potential concerns with a healthcare provider
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