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Dosing, route, and frequency vary by protocol and individual factors such as goals, diet, and medical history
Acid reflux (heartburn): Because GLP-1s slow stomach emptying, heartburn can happen
and (5) outcomesreported at least one outcome we interest, including liver function tests (AST, ALT, -GT), lipid profile tests (HDL cholesterol, LDL cholesterol, total cholesterol, triglyceride), body indicators (BMI, weight, waist circumference), inflammatory factors (hs-CRP), and adverse events
Both the pills and the shot are effective
Two completed Phase 3 trials confirm retatrutide's efficacy: TRIUMPH-4 showed 28.7% average weight loss at 68 weeks, and TRIUMPH-1 confirmed 28.3% in 2,339 general obesity patients at 80 weeks
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