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GLP-1 (Glucagon-Like Peptide-1) is primarily produced in enteroendocrine L-cells located in the distal small intestine (ileum) and colon in response to eating
Two metabolites, coumarin and L-leucine, exhibited higher relative abundance in ASD samples compared to controls, with fold changes of 6.87 (logFC = 2.78) and 3.26 (logFC = 1.71), respectively
Front Biosci 21:13141329
GCL comprises a catalytic (GCLC) and a modifier (GCLM) subunit, and its activity can be readily inhibited with DL-buthionine-sulphoximine (BSO) [13]
GLP-1-related dehydration risk compounds this
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