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Altered gut and adipose tissue hormones in overweight and obese individuals: cause or consequence

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Lifestyle interventions were the least effective treatment, the investigators found, producing a mean total body weight loss of 7.4% at the end of the treatment period, followed by a mean per-month weight regain of 0.14%, with participants reaching their pre-intervention weights within 4.1 years

On a weekly injection, that small variance is clinically insignificant, but precision-minded researchers prefer exact measurements

Most insurers require type 2 diabetes diagnosis or BMI above 30 with comorbid conditions, and many impose prior authorization delays of 48 weeks