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The most commonly reported issue is prolonged fullness or a sensation of excessive abdominal distension
Additional contraception (non-oral or barrier methods) is recommended for 4 weeks after starting treatment and for 4 weeks after each dose increase
exercise then helps convert that caloric deficit into lasting fitness gains rather than purely passive weight loss
Additionally, B12 can help boost energy levels, improve mood, and enhance cognitive function, all of which are important for maintaining an active and fulfilling lifestyle
doi: 10.1056/NEJMoa1003114
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