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Long-term studies on Semaglutide have shown it to be effective in maintaining glycemic control and promoting weight loss over extended periods
2,4 The main safety consideration is dehydration
Semaglutide's cardiovascular benefits come primarily from inflammation reduction, blood pressure lowering, and plaque stabilization rather than cholesterol reduction alone
Table 2 provides a summary of the AGAs recommendations on the management of patients on GLP-1 RAs prior to endoscopy [37]
For dental patients undergoing deep sedation or general anaesthesia, best practices include holding daily GLP-1 agonists on the day of procedure and weekly GLP-1 agonists a week prior to procedure, and adhering to or extending the current ASA fasting guidelines, with the possibility of an addition period of a clear fluid diet ahead of the recommended fasting period
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