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Carvedilol has also been shown to protect against oxidative stress and inflammation in various conditions, such as cardiotoxicity, ulcerative colitis, acute pancreatitis and hepatic ischemia-reperfusion injury
A tryptophan-deficient diet leads to more severe EAE, whereas tryptophan supplementation reverses this effect, suggesting that tryptophan metabolites exert their functions through activation of AhR in microglia
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