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The STEP trials (Semaglutide Treatment Effect in People with obesity) tested weekly semaglutide at 2.4 mg (a higher dose than for diabetes) in people with obesity (BMI 30 or 27+comorbidity)
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Other independent risk factors that may be present in patients taking Wegovy include: Female anatomy and sexual activity Pre-existing diabetes or impaired glucose tolerance Difficulties with perineal hygiene or skin folds Menopausal status and oestrogen deficiency Urinary retention or incomplete bladder emptying Patients experiencing urinary symptoms should be evaluated for these alternative explanations rather than assuming a medication-related cause
Some research protocols employ glucose monitoring to track trends and adjust carbohydrate intake accordingly
