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Indeed, if reduced GSH combines with disulfide bridges on extracellular proteins, it then becomes obvious that its extracellular concentration drops, but then the extracellular GSH concentration takes into account only free GSH, which cannot be used as a reference for GSH excreted by cells
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Adibi SA, Mercer DW
However, little is known whether r-lipoic can be as effective therapy for certain diseases in human, especially the long term effect
In addition, the effect of the new GLP-1 and GIP dual agonist tirzepatide (48) and the combination drug of orlistat and acarbose (49) would be immensely interesting to investigate in adolescents with obesity
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